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Unbox is launching the “Open Minds” project, whose goal is nothing less than restarting the stuck wheels of growth. 

“Open Minds”, managed by the Unbox team, calls experienced entrepreneurs and mentors to turn scientific knowledge and discoveries into future deep-tech ventures, based on mature inventions that are waiting to break out of the campus gates for global impact. 


Prof. Rachela Popovtzer

Dr. Shir Hochwald-Liber

Prof. Ehud Banin

Dr. Yosi Ben-David

Prof. Nitsan Maharshak - Head of IBD Unit at Tel Aviv Medical center

The problem

Crohn’s disease (CD) and ulcerative colitis (UC), also known as Inflammatory Bowel Diseases (IBD), present a major health challenge with a rising incidence worldwide. These chronic gut disorders, marked by recurrent flares, demand early detection and continuous monitoring. Distinguishing them from conditions like Irritable Bowel Syndrome (IBS), which lacks IBD complications, is crucial. Unfortunately, today there is no simple, rapid and non-invasive solution which accurately identifying IBD patients and facilitating early monitoring, hindering optimal disease management. offers bio-chip-based medical device, as a rapid, non-invasive solution for IBD monitoring, effectively distinguishing between IBD and IBS in their very early stages. This innovative technology stands to significantly advance monitoring and management of these complex conditions, paving the way for personalized medicine-based treatment.

The invention technology is based on the ability to detect biological signals secreted by the gut microbiome and evaluate their different presence in IBD conditions. For that end, we combine advanced synthetic biology together with electrochemistry and wireless communication methods to provide rapid, non-invasive, and highly sensitive detection and monitoring of IBD.

Patent- PCT

If you are an experienced entrepreneur willing to establish a knowledge-based venture, click to discover the researchers in our catalog and mark the topics you relate to. Mature researcher-entrepreneur teams would be reviewed by the Unbox investment committee according to our funding model,  and will receive unprecedented terms, including a seed investment, sweeping IP release and professional guidance.

For questions, please contact: Dr. Rotem Efrony

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